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  • Mar 25, 2025 Gelatin vs Vegetarian Capsules: Which One to Choose for Capsule Filling?
    1. Introduction Gelatin and vegetarian capsules are the most common materials for capsule filling in the pharmaceutical and supplement industries, each offering unique benefits. Choosing the right type of capsule is vital for ensuring smooth operation with your capsule filling machine. This guide explores their differences, production requirements, and compatibility with capsule filler machines, helping you make an informed decision.   2. Gelatin vs Vegetarian Capsules: Compatibility with Capsule Filling Machines Both gelatin and vegetarian capsules are widely used in capsule production, but their properties affect how they perform in capsule filling machines. So what is the difference between gelatin capsules and vegetarian capsules? Which one is more compatible with capsule filling equipment? Let’s see some more details of these two empty capsules. 1) What Are Gelatin Capsules? Gelatin capsules are made from gelatin, a protein derived from animal collagen, usually from cows or pigs, and processed into a gel-like consistency for capsule formation. They are commonly used in capsule filler machines for pharmaceuticals and supplements due to their smooth texture and excellent stability.   Types of Gelatin Capsules: • Hard Gelatin Capsules (HGC) Made of two parts (body and cap), these capsules are used for powders, granules, and pellets. Widely used in the applications of vitamins, minerals, herbal supplements, and controlled-release formulations.     • Soft Gelatin Capsules (SGC) One-piece hermetically sealed capsules made from a single piece of gelatin, softgels are sealed to hold liquids or oils, commonly used in fish oil, CBD oil, essential oils, and liquid medications, requiring specialized capsule encapsulation machines.     2) What Are Vegetarian Capsules? Vegetarian capsules, crafted from plant-derived substances such as cellulose or HPMC (hydroxypropyl methylcellulose), serve as a widely used alternative to traditional gelatin capsules. With the help of capsule filling equipment, they are commonly used in dietary supplements like vitamins, minerals, and herbal products. Also widely applied for probiotics and some plant-based medications.     3) Key Differences Between Gelatin and Vegetarian Capsules Here’s a brief comparison to understand these two empty capsules.   Feature Gelatin Capsules Vegetarian Capsules Material Animal-derived gelatin (bovine or porcine). Plant-based materials like HPMC or pullulan. Suitability Not suitable for vegans, vegetarians, or people avoiding animal products. Vegan and vegetarian-friendly. Dissolution 10–20 minutes 20–30 minutes Moisture Resistance Moderate moisture resistance. More susceptible to moisture, affecting stability. Shelf Life Longer, more stable. Shorter, subject to moisture. Storage Requirements Store in cool and dry place to maintain capsule integrity. More sensitive to moisture and humidity. Cost Generally cheaper. ...
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  • Mar 14, 2025 Why Blister Packs Dominate Medical Packaging: 5 Key Advantages
    Have you ever wondered why nearly every prescription medication comes sealed in blister packs? This packaging dominates the pharmaceutical industry for critical reasons that directly impact medication safety, efficacy, and patient outcomes.     The Evolution of Pharmaceutical Packaging Pharmaceutical packaging has undergone significant transformation over the decades. Before the widespread adoption of blister packs, medications were commonly dispensed in glass bottles or paper envelopes, offering minimal protection against environmental factors and providing little assurance of product integrity. The 1960s and 1970s marked a turning point when pharmaceutical companies began prioritizing packaging solutions that could better protect their products while enhancing patient safety. The development of blister packaging technology emerged as a direct response to these growing concerns. By the 1980s, blister packs had gained significant traction in Europe, and by the 1990s, they had become the standard across much of the global pharmaceutical industry. This shift represented a fundamental change in how medications were protected, presented, and consumed.   Current Market Dominance Today, blister packaging represents approximately 85% of solid oral dosage pharmaceutical packaging in Europe and continues to grow in North America. According to recent industry reports, the global pharmaceutical blister packaging market was valued at $23.7 billion in 2023 and is projected to reach $34.2 billion by 2030, growing at a CAGR of 5.4%. This dominance is not arbitrary but rather the result of blister packaging's ability to address critical concerns within the pharmaceutical industry. As regulatory standards have become increasingly stringent and patient safety concerns have grown, blister packs have evolved to meet these challenges, cementing their position as the preferred packaging solution.   Advantage 1: Superior Medication Protection   Moisture and Oxygen Barrier Properties Blister packs excel in creating a protective environment for medications, particularly those sensitive to environmental factors. The sealed cavity formed by the combination of the blister and lidding material serves as a formidable barrier against moisture and oxygen—two primary culprits in pharmaceutical degradation. Modern blister materials offer exceptional barrier properties through multi-layer structures. Typical configurations include: PVC (Polyvinyl Chloride): Provides basic barrier properties PVC/PVDC (Polyvinylidene Chloride): Offers enhanced moisture and oxygen barrier COC (Cyclic Olefin Copolymer): Provides superior moisture protection Aluminum/Aluminum: Creates nearly impermeable barriers for highly sensitive medications A study published in the International Journal of Pharmaceutics demonstrated that properly designed blister packaging can extend the shelf life of moisture-sensitive medications by up to 300% compared to traditional bottle packagin...
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  • Mar 10, 2025 Understanding Types of Pills: The Complete Quick Reference Guide
    When you work in pharmaceutical manufacturing, knowing the types of pills available is essential. This guide helps you navigate the complex world of pill formulations, ensuring you select the right dosage form to meet regulatory standards and consumer expectations. You will learn about tablets, capsules, caplets, lozenges, and more, with detailed insights into each type’s benefits and drawbacks.     The Role of Pills in Pharmaceutical Production Pills are a fundamental form of medication designed to deliver active ingredients efficiently. Their design, composition, and manufacturing processes affect the drug’s performance and consumer compliance. As a professional in the pharmaceutical industry, you need to know how each pill type functions and how it can be optimized for better performance. Each pill type has unique properties: Tablets are compact, solid forms produced by compressing powders. Capsules enclose medication in a dissolvable shell. Caplets combine the shape of capsules with the manufacturing simplicity of tablets. Lozenges dissolve slowly in the mouth for targeted relief. Comprehending these pharmacokinetic and physicochemical distinctions facilitates the rational optimization of manufacturing protocols, thereby ensuring the production of therapeutically effective and chemically stable dosage forms with consistent bioavailability profiles. Overview of Pill Classifications Pharmaceutical pills are generally categorized by their form, release characteristics, and administration routes. The main categories include: Tablets Tablets are the most common dosage form in pharmaceuticals. They are manufactured by compressing powders into a solid form. Solid oral dosage forms may be engineered with distinct release kinetics profiles, including immediate-release (IR), modified-release (MR), and delayed-release (DR) configurations, with formulations tailored to achieve target pharmacokinetic parameters and therapeutic outcomes.. They are favored for their stability, ease of production, and dosage accuracy. Capsules Capsules consist of a shell, typically made of gelatin or HPMC (hydroxypropyl methylcellulose), that encloses powdered or liquid medication. They provide advantages like masking unpleasant tastes and protecting sensitive ingredients. Capsules are ideal when precise dosing is required, and they offer flexibility in terms of dosage form. Caplets Caplets combine the advantages of tablets and capsules. They are oval-shaped and coated, making them easier to swallow while still offering the manufacturing efficiency of tablets. Caplets are popular when patient compliance is a key concern. Lozenges Lozenges are formulated for gradual dissolution in the mouth, enabling targeted delivery of active ingredients to the site of action. They are especially useful for localized treatments, such as soothing a sore throat, and are formulated to maintain a prolonged effect. Orally Disintegrating Tablets (ODTs) ODTs are designed to d...
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  • Feb 17, 2025 The Complete Guide to Blister Pack Materials: PVC, PET, or Aluminum?
    Introduction In the pharmaceutical and consumer goods industries, packaging plays an essential role in ensuring the safety, efficacy, and convenience of products. When it comes to blister packs, the material choice is one of the most critical aspects of packaging design. Blister packs are widely used for packaging a variety of products, from tablets and capsules to medical devices, food items, and even cosmetics. In this comprehensive guide, we’ll explore the three most common blister pack materials—PVC, PET, and Aluminum—and discuss their respective advantages and disadvantages. By understanding the unique properties of each material, you’ll be able to make an informed decision when selecting the best option for your packaging needs.     What Is a Blister Pack? A blister pack is a pre-formed plastic packaging type, often used for pharmaceutical tablets and capsules, where each dose is sealed in a cavity or blister. The blister itself is typically made of a plastic material, while the backing is generally made from aluminum or paperboard. Blister packs provide a secure, tamper-evident, and protective seal around the product, preventing exposure to moisture, light, and air—critical factors in preserving the stability of sensitive products. Blister packs are used in various industries, including pharmaceuticals, consumer goods, food, and cosmetics. The material selected for a blister pack determines the level of protection, cost-effectiveness, and consumer experience. In the following sections, we’ll focus on the three primary materials used for blister packs: PVC (Polyvinyl Chloride), PET (Polyethylene Terephthalate), and Aluminum.   PVC (Polyvinyl Chloride) Blister Packs Overview of PVC PVC, or Polyvinyl Chloride, is one of the most commonly used materials for blister packaging due to its cost-effectiveness, versatility, and ease of use. PVC is a plastic polymer that can be rigid or flexible, depending on the formulation. It is widely used for blister packs in the pharmaceutical and consumer goods industries. Advantages of PVC Blister Packs 1. Cost-Effectiveness: PVC is an affordable material compared to other blister pack materials. Its low cost makes it an ideal choice for high-volume production. 2. Excellent Formability: PVC is highly versatile and can be easily molded into various shapes and sizes. This flexibility allows manufacturers to create blister packs that fit specific product requirements. 3. Clarity and Transparency: PVC offers high clarity, allowing the consumer to clearly see the product inside the blister pack. This transparency is especially useful in consumer goods packaging, where product visibility is important. 4. Good Barrier Properties: PVC provides a basic level of protection against moisture and contaminants, making it suitable for less sensitive pharmaceutical products. 5. Ease of Sealing: PVC is easy to seal with aluminum foil or other bac...
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  • Jan 15, 2024 Buying Tablet Capsule Counting Machines from China?
    With the demand of the tablet and capsules machines in the market, there is a trend that more and more businesses are turning to buy from Chinese suppliers. What’s the reason? As the pharmaceutical and nutraceutical industries demand greater precision, efficiency, and scalability,tablet and capsule counting technology has advanced significantly. In this article, we will explore the reason when selecting tablet capsule counting machines, why Chinese suppliers are gaining popularity, and how to choose the right manufacturer to stay competitive and compliant.      1. Why People Are Turning to Chinese Suppliers for Tablets Capsules Counting Machine Choosing a tablet and capsule counting machine is not difficult once you have a clear idea what you want for your production line, but choosing the right supplier is not as easy. Among so many countries across the world, China has become one of the largest and most reliable hubs for manufacturing automated machinery, including tablet and capsule counting machines. But why businesses are increasingly sourcing their equipment from China? Here below we will discuss some key factors including competitive pricing, manufacturing scales and capacity, efficient production and lead times as well as strong after-sales support.   • Competitive Pricing Chinese manufacturers have a significant cost advantage due to lower labor costs, economies of scale, and an efficient supply chain. A report indicates that manufacturing costs in China are 30-40% lower compared to those in the United States or Europe. This cost advantage makes Chinese suppliers an appealing choice for companies seeking to lower capital expenses while maintaining high quality. For pharmaceutical products production, especially pills and tablets, manufacturers may need the whole production line which can cost millions of dollars easily. But if you switch to the Chinese supplier, you will be able to save a huge cost in this case. That’s why it’s so tempting for the businesses to look for solutions from China.   • Manufacturing Scale and Capacity According to THE NEW ERA OF CHINESE MANUFACTURING published by Canada China Business Council, China has emerged as a global manufacturing leader, contributing 31.7% to its GDP in 2023. It continues to be a dominant force in the global market, accounting for 28.4% of the world's total manufacturing output. This scale allows manufacturers to produce large volumes of machines, meaning faster delivery times and the ability to meet varying demands for large or small-scale production. In this case, getting the automated production lines from China could be faster than getting from customers’ own country which require more time for the production and delivery. The advantage of buying from local country may seem less competitive.     • Efficient Production and Lead Times China's robust manu...
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  • Feb 11, 2025 The Rise of Tablet Capsule Counters in Pharma Industry
    In the ever-evolving pharmaceutical industry, the demand for pharmaceuticals and dietary supplements continues to rise and the role of tablet and capsule counting machines has grown significantly. Capsule Tablet Counters are no longer just a convenience, they are also part of the modern pharmaceutical production process. In this article, we will explore the current trend of tablet capsule counters as well as the reason of the increasing demand.       1. Current Market Trend for Tablet Capsule Counting Machines First of all, for the idea that the current demand of tablet capsule counting machines is increasing, it is not an assumption but a conclusion based on statistics of some research. As reported by MarketsandMarkets, the global pharmaceutical packaging equipment sector was valued at $8.9 billion in 2023 and is anticipated to grow to $12.4 billion by 2028, reflecting a compound annual growth rate (CAGR) of 7.0%. One of the key factors driving this growth is the rising demand for automation in production processes, which plays a critical role in industries such as pharmaceuticals, food production, and dietary supplements.      Among this automation production, tablet capsule counting machines are part of the key equipment in this market. Key drivers of this market growth include: • Rising Demand for Pharmaceuticals and Supplements: Aging populations and growing health awareness have significantly increased the need for both prescription drugs and dietary supplements, requiring more efficient and precise packaging solutions. • Advancements in Automation: Automation in tablet and capsule counting has enabled faster, more accurate production lines, reducing human error and increasing overall efficiency. • Regulatory Compliance: Pharmaceutical manufacturers must adhere to strict regulations, including FDA and GMP standards. Automated counting ensures accurate, compliant packaging, safeguarding consumer health and maintaining regulatory compliance.        2. Key Reasons for the Rise of Tablet Capsule Counters 1) Precision and Accuracy  The most crucial role of tablet and capsule counting machines is their ability to deliver precise and accurate counting results. Pharmaceutical production lines must meet regulatory requirements, and any errors in counting can lead to serious safety concerns, recalls, or penalties. These machines eliminate human error, ensuring that each bottle has the exact number of tablets or capsules as required. Advanced technologies such as photoelectric sensors and CCD cameras are integrated into modern tablet counters to ensure high-precision counting, regardless of tablet size or shape. This capability is especially vital for pharmaceutical products where consumer safety and regulatory compliance are critical. 2) Speed and Efficiency Tablet and capsule counting machines are...
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  • Feb 07, 2025 How to Press Pills? A Complete Guide to Tablet Production
    Have you ever wondered about the process of tablet production or pill pressing? It is a meticulous process vital for creating pharmaceuticals and other tablets. In this article, we will outline the process of pill pressing step-by-step, from raw material preparation to final quality checks, offering essential insights for manufacturers aiming for excellence.     1. Pill Pressing Ingredient Preparation Every great product starts with high-quality ingredients, and tablet production is no exception. Proper preparation ensures the materials are ready for the next step, paving the way for consistent and high-quality results. Here below are some key points that you need to consider when preparing the ingredients. • Raw Material Inspection: Before anything else, the raw materials must be carefully inspected to ensure they meet the required standards. Each ingredient should be evaluated for purity, moisture content, and particle size. Any inconsistencies at this stage can lead to poor-quality tablets. • Blending and Mixing: Once the materials pass inspection, they need to be blended uniformly. Homogeneous mixing ensures that each pill contains the correct proportions of active ingredients and excipients. This is particularly critical for pharmaceutical products, where dosage accuracy is non-negotiable. • Granulation (if required): In some cases, powders may need to be granulated to improve their flowability. Granulation converts the fine powders into larger, free-flowing granules, which are easier to compress into tablets. There are some machines such as dry granulators and wet granulators that are designed specially for this purpose.  2. Choosing the Right Tablet Press Machine Choosing the right tablet press machine is crucial for achieving production goals while ensuring the quality and consistency of the final product. The machine you select should align with your specific production needs, material properties, and operational requirements. So what kind of machine shall you choose? Here’s how to make the right decision. 1) Single Punch VS Automatic Rotary Tablet Press When choosing a tablet press machine, it’s essential to understand your needs of production in terms of production capacity, flexibility or other special requirements. According to various production speed, below are the two major types of tablet press machines commonly seen in the market.       • Single Punch Tablet Press: Best for small-scale or experimental production with lower costs and simpler operation. This type of tablet press machine also come with semi-automatic or fully automatic options depends on customers’ requirements. • Automatic Rotary Tablet Press: Ideal for medium to large-scale production with high-speed output, automated precision, and consistent quality. Usually this type of pill pressing machine com...
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  • Feb 07, 2025 Tablets VS capsules. Which is a better option?
     If you need medicines or dietary supplements to cure your disease or improve your health status, capsules and tablets are the most usually seen oral dosage forms, and they are important options that effect the way medications are absorbed in your body.       Tablet or capsule? When it comes to the issue of tablets vs capsules, we need to make a rational decision. Outwardly, capsules and tablets are different in their shapes and sizes, and they also differ in the aspects of swallowing difficulty, dissolvability, internal availability, sensitivity to environment, etc. This essay will analyze benefits and drawbacks of capsules and tablets, helping you make a better choice when facing the two options.   What Are Capsules?         Knowing basic knowledge of capsules and tablets is essential for you to understand the difference between capsule and tablet.   There are two main types of capsule: hard-shell capsules and soft-shell capsules, respectively used for containing powdered or granular ingredients, and containing liquid formulations. A majority of capsule shells are made of gelatin, while others are made of vegetable (friendly to vegetarians). Samples of these capsule types are shown in pictures below.   No matter what kind of shell is, both hard shells and soft shells are digestible, letting powder and granules enclosed in capsule shells be released in your body. Capsules are soluble, ideal for containing medications which need a rapid efficacy.       Capsules contain mainly medical or health supplement ingredients. Compared to tablets, capsules have less inactive components, to some degree reducing drug allergy. A significant benefit is that capsules are easier to swallow with water.   What Are Tablets?       Tablets are a solid dosage form for the most frequent use in pharmaceutical and health supplement industries. Typically, tablets are small, round or oval objects produced to be ingested orally. They are produced by compressing powder into solid pieces of different shapes and sizes.   In terms of composition, tablets mainly contain active pharmaceutical ingredients— the “API”, while other components include fillers (for increasing the tablet bulk especially when API is of a small amount), binders (for holding a tablet together), disintegrants (help a tablet break apart in gastrointestinal tracts, releasing API), lubricants (for reducing friction between tablets and the equipment at production stages), and coatings (for improving flavors or protecting tablets from dissolving in the stomach).   Tablets are easy to be taken along, and it’s convenient to carry them in a paper box or a plastic container. Not susceptible to moisture and light, tablets are unlikely to decay when being exposed to air, offering longer shelf life and higher stability compared to capsules or liquid drugs.   Comparing capsules and tablets, wh...
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  • Feb 07, 2025 What Are Different Levels and Types of Pharmaceutical Packaging?
    Different levels and types of Pharmaceutical packaging means a lot to medical and pharmaceutical industries, protecting medications from being damaged by environmental factors such as light, heat, humidity and other forms of contamination. It can also prevent medications from being tampered.       The packaging plays a vital role in ensuring the safety, effectiveness and quality stability of medicines and drugs. This article will show different levels and types of pharmaceutical packaging, followed by their benefits, describing how the medicine packaging is achieved.   What are different levels of pharmaceutical packaging? Three levels exist when it comes to medicine package. They are primary, secondary and tertiary pharmaceutical packaging.       Primary Packaging Produced to protect medicines’ quality and chemical composition, primary packaging refers to the material that makes direct contact with pharmaceuticals. There are some kinds of this material, such as a container of pills.   Tablets and capsules are mostly stored in blister packs and bottles, while liquid drugs are often packaged in ampoules and vials.   · Blister packs: are typically seen in forms of aluminum-PVC and aluminum-aluminum blister packs. They provide individual compartments for each capsule, tablet or pill, protect pharmaceutical products by providing a shelter against humidity, dust and other kinds of contaminant, for medications need a stable condition to keep their efficacy. In terms of product integrity, the design of blister packs is to be tamper-evident. If a blister is used or opened, it’s difficult to restore it, ensuring the product integrity and strengthening consumers’ confidence that their pills have not ever been tampered.     ( Blister packs )   · Pill bottles: contain solid medicines like capsules and tablets, and sometimes contain liquid drugs. These bottles are commonly made of plastic or glass, and glass bottles are mostly in brown or orange for protecting content from ultraviolet light.   ( Pill bottles )   · Sachets: are small, sealed pouches or packets used to package powdered or granular medications and health supplements. They are lightweight and easy to take along with, offering portability and convenience of use.     ( Sachets )   · Soft tubes: contain liquid drugs like eyedrops and unguent. · Vials: are small glass containers for medicine, usually containing medicines in the form of liquid or powder.     ( Vials )   · Ampoules: are smaller glass containers, produced to contain a very small number of liquid drugs used for an injection.   ( Ampoule )   Secondary Packaging Secondary packaging refers to containers that protect the primary packaging material, and provide information of pharma’s branding and medicine use directions on the su...
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